Evaluation of Daily Oral PrEP as a Primary Prevention Strategy for Young African Women: A Vanguard Study : HPTN 082

Study objectives

The primary objectives of HPTN 082 this study are:

To assess the proportion and characteristics of young HIV-uninfected women who accept versus decline PrEP at enrollment.

To assess the difference in PrEP adherence using drug levels in young women randomized to the enhanced versus standard arms.

Modelling objectives

As this study is not powered to measure the effectiveness of the intervention on HIV incidence, we will assess the potential impact of PrEP use on HIV acquisition in young African women through mathematical modelling using the trial data on sexual behaviour, uptake and adherence.

 

 

Collaborators

Additional Funding

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